Red Factor (RED FACTOR)
Red/Black Factor, Black/Red Factor, Extension (E)
All horses have a base coat of either black or red pigment which is controlled by mutations in two genes. The Red Factor (RED FACTOR) gene determines the distribution of red pigment in a horse’s coat. If a horse carries two copies of the Red Factor mutation, they will exhibit a uniformly distributed red coat color regardless of their Agouti status. Horses with a single copy or no copy of the Red Factor mutation can be affected by two copies of the Agouti mutation which leads to a uniformly distributed black coat.
Reading Your Results
A. (CLEAR/NORMAL):
These horses have two copies of the normal gene and will neither develop a uniformly distributed red coat color nor pass this mutation to their offspring.
B. (CARRIER/NOT AFFECTED):
These horses have one copy of the normal gene and one copy of the mutation associated with this coat color. They will not develop a uniformly distributed red coat color and will, if bred, pass the mutation to 50% of its offspring, on average.
C. (AT RISK/AFFECTED):
These horses have two copies of the mutation associated with uniformly distributed red pigment which typically results in a red base coat color.
Available For:
- Horse
- American Paint Horse
- American Quarter Horse
- Appaloosa
- Appendix
- Arabian
- Australian Stock Horse
- Belgian
- Cob Normand
- Exmoor Pony
- Haflinger
- Miniature Horse
- Missouri Fox Trotter
- Morgan
- Mustang
- Noriker
- Percheron
- Pony of the Americas
- Rhenish German Coldblood
- Rocky Mountain Horse
- Saxon-Thuringian Coldblood
- Shire
- South German Coldblood
- Tennessee Walking Horse
- Thoroughbred
Additional Details
Inheritances
Autosomal Recessive
Affected gene
MC1R
Chromosome
Ch. 3
Mutation
c.901 C>T; p.S83F
Publication:
Rieder S, Taourit S, Mariat D, Langlois B, Guérin G. Mutations in the agouti (ASIP), the extension (MC1R), and the brown (TYRP1) loci and their association to coat color phenotypes in horses (Equus caballus). Mamm Genome. 2001;12(6):450-455. [PubMed: 11353392]
