This disease is characterized by the excretion of uric acid leading to the formation of urinary calculi (stones) which may then require surgery. If a dog from a breed susceptible to this disorder is seen to experience problems urinating freely, then veterinary advice should be sought immediately.
American Staffordshire Terrier
Black Russian Terrier
Coton De Tulear
German Shepherd Dog
Jack Russell/Parsons Terrier
South African Boerboel
A (CLEAR/NORMAL): These dogs have two copies of the normal gene and will neither develop urate stone disorder nor pass this mutation to their offspring.
B (CARRIER/NOT AFFECTED): These dogs have one copy of the normal gene and one copy of the mutation associated with this disease. They will not develop urate stone disorder but will, if bred, pass the mutation to 50% of its offspring, on average.
C (AT RISK/AFFECTED): These dogs have two copies of the mutation associated with this disease and are susceptible to develop bladder/kidney stones.
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