Canine Factor VII Deficiency (CFVII)
Factor VII is a clotting factor synthesized in the liver that is necessary to initiate blood coagulation when vascular injury occurs. The condition is not fatal but can cause increased bleeding after surgery or injury in affected dogs. In rare circumstances, an affected dog may experience excessive bleeding and require a blood transfusion.
- Alaskan Klee Kai
- Giant Schnauzer
- Scottish Deerhound
A (CLEAR/NORMAL): These dogs have two copies of the normal gene and will neither develop factor VII deficiency nor pass this mutation to their offspring.
B (CARRIER/NOT AFFECTED): These dogs have one copy of the normal gene and one copy of the mutation associated with this disease. They will not develop factor VII deficiency but will, if bred, pass the mutation to 50% of its offspring, on average.
C (AT RISK/AFFECTED): These dogs have two copies of the mutation associated with this disease and are susceptible to develop problems with blood clotting.