PRA-CORD1-CRD4 Genetic Test | GenSol Diagnostics

Border Collie Glaucoma (BCG)


Glaucoma is a painful and potentially blinding disease associated with high eye pressure that can be caused by an improper drainage system within the eye. Lack of fluid drainage can lead to increased fluid pressure inside the eye and subsequent damage to the optic nerve potentially leading to a total loss of vision. Symptoms of the disease can include severe pain, light sensitivity, eye spasms and watery eyes. Dogs suffering from the condition may display behaviors such as hiding, refusal to eat and defensive head movements in response to painful symptoms. It is important to note that the test offered detects a ‘candidate’ mutation that has been strongly associated with glaucoma in Border Collies but will require additional research to demonstrate a conclusive connection to the disease. Nevertheless, the current ‘candidate” mutation test can provide value in assisting with breeding decisions.

Border Collie

A (CLEAR/NORMAL): These dogs have two copies of the normal gene and will neither develop BCG nor pass this mutation to their offspring.

B (CARRIER/NOT AFFECTED): These dogs have one copy of the normal gene and one copy of the mutation associated with this disease. They will not develop BCG but will, if bred, pass the mutation to 50% of its offspring, on average.

C (AT RISK/AFFECTED): These dogs have two copies of the mutation associated with this disease which will likely result in eye drainage issues, pressure buildup within the eye and potential loss of vision.

Border Collie Glaucoma (BCG)

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